The Trans-Siberian Express is a train route which runs from Moscow to Ussuriysk via Ekaterinburg, Omsk, Irkutsk and Karimskaya. Stretching across the entire length of Russia, the Trans-Siberian Express is the longest train route in the game.

Favored by the rich and the poor alike, Passepartout meets many interesting people on his journey aboard the train, including a Mongolian Princess named Goland who is studying to be an engineer, and a wealthy debutante named Roza who is having an illicit affair with a boy in the lower-class carriage, as well as one of the train's chief engineers and his bodyguard.

The Trans-Siberian can be sped up by talking to a man on board the "Gallant Rider" from Vienna to Warsaw, who will tell you that the Trans-Siberian can travel faster than a normal train because it has the ability to levitate with magnets. With this information, one can speed up the train significantly.